简介
Summary:
Publisher Summary 1
Incorporating work from 178 contributors affiliated with 43 centers in nine countries, editors Mundt and Roeske (both: radiation and cellular oncology, U. of Chicago) begin this text with the fundamentals, giving an in-depth overview of the physics, biology, and medicine pertaining to this rapidly developing therapy. Following is a systematic exploration of the steps and technologies for planning, delivery, and clinical implementation; an overview of commercially available inverse planning and delivery systems; and an overview of the application of IMRT in all clinical sites. Each disease is presented in detail, along with considerations in treatment planning and review of published IMRT literature. Overview chapters are paired with case studies--each dealing with simulation, immobilization, target delineation, plan optimization and delivery, and quality assurance of an actual patient. Finally, the book concludes with commentaries on proton IMRT, the combination of IMRT and biological modifiers and the pros and cons of IMRT. The included CD-ROM includes the text and illustrations of the book in searchable PDF format. Annotation 漏2006 Book News, Inc., Portland, OR (booknews.com)
目录
Table Of Contents:
Foreword xi
Preface xiv
Contributors xvii
I. Fundamentals
IMRT Process 1(19)
Arno J. Mundt
Philip M. Bruch
Brenda Wyman
Carmelita Chotipradit
John C. Roeske
Physics of IMRT 20(33)
Lei Xing
Qiuwen Wu
Yong Yang
Arthur L. Boyer
Radiobiology of IMRT 53(22)
Joseph O. Deasy
Jack F. Fowler
Medicine of IMRT 75(8)
Bahman Emami
II. Technology and Implementation
CT Simulation 83(8)
Tim Fox
Elizabeth Butker
Eric Elder
Immobilization and Localization 91(6)
James Balter
Imaging and Fusion Technologies 97(18)
Charles A. Pelizzari
Anthony E. Lujan
PET-CT in IMRT Planning 115(16)
Jeffrey T. Yap
David W. Townsend
Nathan C. Hall
Respiratory Motion Management 131(18)
John Wong
Geoff Hugo
Gikas Mageras
Ellen Yorke
Treatment Planning 149(17)
Russell J. Hamilton
Martin E. Lachaine
Benjamin Armbruster
Plan Evaluation 166(12)
Todd Pawlicki
Quynh-Thu Le
Christopher King
Delivery Systems 178(8)
Cheng B. Saw
Komanduri M. Ayyangar
Komanduri V. Krishna
Andrew Wu
Shalom Kalnicki
Commissioning and Dosimetric Quality Assurance 186(12)
Joseph Ting
Quality Assurance Processes and Future Directions 198(6)
Daniel A. Low
Eric E. Klein
IMRT in the Community Setting 204(10)
Norman Lehto
Brent Murphy
Peter Lai
Billing and Reimbursement 214(17)
Chet Szerlag
Luis Canovas
III. Clinical Topics and Case Studies
Central Nervous System Tumors: Overview 231(33)
Volker W. Stieber
Michael T. Munley
Meningioma: Case Study 242(5)
Andrea Pirzkall
Base of Skull Tumor: Case Study 247(6)
Marc W. Munter
Jurgen Debus
Glioblastoma Multiforme: Case Study 253(4)
Minoru Suzuki
Masahiko Okumura
Yasumasa Nishimura
Intensity-Modulated Radiosurgery: Emerging Technology 257(7)
Stanley H. Benedict
Robert M. Cardinale
Danny Song
Head and Neck Cancer: Overview 264(80)
Avraham Eisbruch
Nasopharyngeal Cancer: Case Study 276(8)
William W. Chou
Nancy Y. Lee
Ethmoid Sinus Cancer: Case Study 284(5)
Filip Claus
Wim Duthoy
Wilfried De Neve
Maxillary Sinus Cancer: Case Study 289(4)
Bahman Emami
Stephanie King
Anil Sethi
Guy Petruzzelli
Base of Tongue Cancer: Case Study 293(8)
Quynh-Thu Le
Todd Pawlicki
Pyriform Sinus Cancer: Case Study 301(6)
Michael T. Milano
Wells Jackson
Daniel J. Haraf
Functional Imaging in Head and Neck Cancer: Emerging Technology 307(12)
Thomas Yang
K. S. Clifford Chao
Simultaneous Integrated Boost: Emerging Technology 319(8)
Qiuwen Wu
Radhe Mohan
Modulated Electron Radiation Therapy: Emerging Technology 327(10)
Yulin Song
Arthur L. Boyer
Todd Pawlicki
Steve Jiang
Yulong Yan
C. --M. Charlie Ma
Lei Xing
Impact of Prolonged Treatment Times: Emerging Technology 337(7)
Steven J. Chmura
Karl Farrey
Steve Wang
Michael C. Garofalo
John C. Roeske
Lung Cancer: Overview 344(42)
Craig W. Stevens
Thomas Guerrero
Kenneth M. Forster
George Starkschall
Reginald Munden
Target Definition in Non-Small Cell Lung Cancer: Case Study 358(8)
Thomas Guerrero
Yerko Borghero
Craig W. Stevens
Synchronous Bilateral Non-Small Cell Lung Cancer: Case Study 366(7)
Thomas Guerrero
Stephen Bilton
Craig W. Stevens
Helical Tomotherapy for Lung Cancer: Emerging Technology 373(3)
Scott P. Tannehill
Hazim A. Jaradat
Intrafractional Organ Motion and Planning: Emerging Technology 376(10)
Jong H. Kung
Piotr Zygmanski
George T. Y. Chen
Breast Cancer: Overview 386(28)
Frank A. Vicini
Douglas Arthur
John Wong
Larry Kestin
Intact Breast Cancer: Case Study 393(5)
Frank A. Vicini
Douglas Arthur
John Wong
Larry Kestin
Accelerated Concomitant Boost: Emerging Technology 398(9)
Eugene P. Lief
J. Keith DeWyngaert
Stella C. Lymberis
Silvia C. Formenti
Real-Time-3D-Video-Guided IMRT: Emerging Technology 407(7)
Shidong Li
Jason Geng
Gastrointestinal Tumors: Overview 414(22)
Michael C. Garofalo
Steven J. Chmura
Pancreatic Cancer: Case Study 423(4)
Jerome Landry
Natia Esiashvili
Mary Koshy
Rectal Cancer: Case Study 427(5)
Javier Aristu
Juan D. Azcona
Marta Moreno
Rafael Martinez-Monge
Anal Cancer: Case Study 432(4)
Anthony M. Berson
Gregory M. Richards
Richard Emery
Intact Prostate Cancer: Overview 436(13)
Alan Pollack
Robert Price
Lei Dong
Steven J. Feigenberg
Eric M. Horwitz
Postoperative Prostate Cancer: Overview 449(43)
Bin S. Teh
Thomas M. Schroeder
Wei-Yuan Mai
E. Brian Butler
Intact Prostate Cancer: Case Study 459(5)
Robert A. Price Jr
Eric M. Horwitz
Steven J. Feigenberg
Alan Pollack
Hypofractionated IMRT: Case Study 464(3)
Patrick Kupelian
Twyla Willoughby
Targeted Lymph Node Irradiation: Case Study 467(8)
Steven L. Hancock
Todd Pawlicki
Raymond Tan
ProstaScint-Guided IMRT: Case Study 475(6)
Ashesh B. Jani
John C. Roeske
Intra-Prostatic Boost: Emerging Technology 481(5)
Maria T. Guerrero Urbano
Catharine Clark
Chris M. Nutting
David P. Dearnaley
Repair of Unacceptable Implants: Emerging Technology 486(6)
X. Allen Li
Jian Z. Wang
Gynecologic Cancer: Overview 492(43)
Loren K. Mell
John C. Roeske
Neil Mehta
Arno J. Mundt
Cervical Cancer: Case Study 506(7)
Tracey E. Schefter
Brian D. Kavanagh
Endometrial Cancer: Case Study 513(5)
Anuja Jhingran
Mohammad Salehpour
Brooke Brooks
Cervical Cancer Not Suitable for Brachytherapy: Case Study 518(5)
Philip Chan
Michael Milosevic
Janet Paterson
Inhwan Yeo
Anthony W. Fyles
Bone Marrow-Sparing IMRT: Emerging Technology 523(8)
John C. Roeske
Anthony E. Lujan
Arno J. Mundt
Applicator-Guided IMRT: Emerging Technology 531(4)
Daniel A. Low
Lymphoma: Overview 535(21)
Billy W. Loo Jr
Richard T. Hoppe
Hodgkin's Disease: Case Study 547(6)
Billy W. Loo Jr
Richard T. Hoppe
Helical Tomotherapy
A New Mantle: Emerging Technology 553(3)
James S. Welsh
Christopher Peterson
Brad Kahl
Gustavo Olivera
Sarcoma: Overview 556(17)
Kaled M. Alektiar
Linda Hong
Paraspinal Soft Tissue Sarcoma: Case Study 562(6)
Brian O'Sullivan
Ramani Ramaseshan
Mohammad Islam
Robert Heaton
Retroperitoneal Sarcoma: Case Study 568(5)
John B. Fiveash
Richard A. Popple
Martin J. Heslin
Pediatric Tumors: Overview 573(20)
Shiao Y. Woo
Retinoblastoma: Case Study 579(5)
Robert S. Lavey
Arthur J. Olch
Neuroblastoma: Case Study 584(4)
Robert S. Lavey
Arthur J. Olch
Rhabdomyosarcoma: Case Study 588(5)
Joseph K. Salama
Philip P. Connell
Metastatic and Recurrent Tumors: Overview 593(22)
Johnny Kao
Arno J. Mundt
Recurrent Spinal Metastasis: Case Study 599(5)
Stefanie Milker-Zabel
Recurrent Nasopharyngeal Cancer: Case Study 604(5)
Wei-Yuan Mai
Tai-Xiang Lu
Xiao-Wu Deng
Intensity-Modulated Radiosurgery for Spinal Metastasis: Emerging Technology 609(6)
Fang-Fang Yin
Samuel Ryu
Jae Ho Kim
IV. Invited Commentaries
Intensity-Modulated Proton Therapy 615(7)
Tony Lomax
Eros Pedroni
Doelf Coray
Gudrun Goitein
Martin Jermann
Biologic Modifiers and IMRT 622(6)
Kenneth Dornfeld
John Buatti
Pros and Cons of IMRT: What's Been Swept Under the Rug? 628(11)
Roberto J. Santiago
Eli Glatstein
Index 639
Foreword xi
Preface xiv
Contributors xvii
I. Fundamentals
IMRT Process 1(19)
Arno J. Mundt
Philip M. Bruch
Brenda Wyman
Carmelita Chotipradit
John C. Roeske
Physics of IMRT 20(33)
Lei Xing
Qiuwen Wu
Yong Yang
Arthur L. Boyer
Radiobiology of IMRT 53(22)
Joseph O. Deasy
Jack F. Fowler
Medicine of IMRT 75(8)
Bahman Emami
II. Technology and Implementation
CT Simulation 83(8)
Tim Fox
Elizabeth Butker
Eric Elder
Immobilization and Localization 91(6)
James Balter
Imaging and Fusion Technologies 97(18)
Charles A. Pelizzari
Anthony E. Lujan
PET-CT in IMRT Planning 115(16)
Jeffrey T. Yap
David W. Townsend
Nathan C. Hall
Respiratory Motion Management 131(18)
John Wong
Geoff Hugo
Gikas Mageras
Ellen Yorke
Treatment Planning 149(17)
Russell J. Hamilton
Martin E. Lachaine
Benjamin Armbruster
Plan Evaluation 166(12)
Todd Pawlicki
Quynh-Thu Le
Christopher King
Delivery Systems 178(8)
Cheng B. Saw
Komanduri M. Ayyangar
Komanduri V. Krishna
Andrew Wu
Shalom Kalnicki
Commissioning and Dosimetric Quality Assurance 186(12)
Joseph Ting
Quality Assurance Processes and Future Directions 198(6)
Daniel A. Low
Eric E. Klein
IMRT in the Community Setting 204(10)
Norman Lehto
Brent Murphy
Peter Lai
Billing and Reimbursement 214(17)
Chet Szerlag
Luis Canovas
III. Clinical Topics and Case Studies
Central Nervous System Tumors: Overview 231(33)
Volker W. Stieber
Michael T. Munley
Meningioma: Case Study 242(5)
Andrea Pirzkall
Base of Skull Tumor: Case Study 247(6)
Marc W. Munter
Jurgen Debus
Glioblastoma Multiforme: Case Study 253(4)
Minoru Suzuki
Masahiko Okumura
Yasumasa Nishimura
Intensity-Modulated Radiosurgery: Emerging Technology 257(7)
Stanley H. Benedict
Robert M. Cardinale
Danny Song
Head and Neck Cancer: Overview 264(80)
Avraham Eisbruch
Nasopharyngeal Cancer: Case Study 276(8)
William W. Chou
Nancy Y. Lee
Ethmoid Sinus Cancer: Case Study 284(5)
Filip Claus
Wim Duthoy
Wilfried De Neve
Maxillary Sinus Cancer: Case Study 289(4)
Bahman Emami
Stephanie King
Anil Sethi
Guy Petruzzelli
Base of Tongue Cancer: Case Study 293(8)
Quynh-Thu Le
Todd Pawlicki
Pyriform Sinus Cancer: Case Study 301(6)
Michael T. Milano
Wells Jackson
Daniel J. Haraf
Functional Imaging in Head and Neck Cancer: Emerging Technology 307(12)
Thomas Yang
K. S. Clifford Chao
Simultaneous Integrated Boost: Emerging Technology 319(8)
Qiuwen Wu
Radhe Mohan
Modulated Electron Radiation Therapy: Emerging Technology 327(10)
Yulin Song
Arthur L. Boyer
Todd Pawlicki
Steve Jiang
Yulong Yan
C. --M. Charlie Ma
Lei Xing
Impact of Prolonged Treatment Times: Emerging Technology 337(7)
Steven J. Chmura
Karl Farrey
Steve Wang
Michael C. Garofalo
John C. Roeske
Lung Cancer: Overview 344(42)
Craig W. Stevens
Thomas Guerrero
Kenneth M. Forster
George Starkschall
Reginald Munden
Target Definition in Non-Small Cell Lung Cancer: Case Study 358(8)
Thomas Guerrero
Yerko Borghero
Craig W. Stevens
Synchronous Bilateral Non-Small Cell Lung Cancer: Case Study 366(7)
Thomas Guerrero
Stephen Bilton
Craig W. Stevens
Helical Tomotherapy for Lung Cancer: Emerging Technology 373(3)
Scott P. Tannehill
Hazim A. Jaradat
Intrafractional Organ Motion and Planning: Emerging Technology 376(10)
Jong H. Kung
Piotr Zygmanski
George T. Y. Chen
Breast Cancer: Overview 386(28)
Frank A. Vicini
Douglas Arthur
John Wong
Larry Kestin
Intact Breast Cancer: Case Study 393(5)
Frank A. Vicini
Douglas Arthur
John Wong
Larry Kestin
Accelerated Concomitant Boost: Emerging Technology 398(9)
Eugene P. Lief
J. Keith DeWyngaert
Stella C. Lymberis
Silvia C. Formenti
Real-Time-3D-Video-Guided IMRT: Emerging Technology 407(7)
Shidong Li
Jason Geng
Gastrointestinal Tumors: Overview 414(22)
Michael C. Garofalo
Steven J. Chmura
Pancreatic Cancer: Case Study 423(4)
Jerome Landry
Natia Esiashvili
Mary Koshy
Rectal Cancer: Case Study 427(5)
Javier Aristu
Juan D. Azcona
Marta Moreno
Rafael Martinez-Monge
Anal Cancer: Case Study 432(4)
Anthony M. Berson
Gregory M. Richards
Richard Emery
Intact Prostate Cancer: Overview 436(13)
Alan Pollack
Robert Price
Lei Dong
Steven J. Feigenberg
Eric M. Horwitz
Postoperative Prostate Cancer: Overview 449(43)
Bin S. Teh
Thomas M. Schroeder
Wei-Yuan Mai
E. Brian Butler
Intact Prostate Cancer: Case Study 459(5)
Robert A. Price Jr
Eric M. Horwitz
Steven J. Feigenberg
Alan Pollack
Hypofractionated IMRT: Case Study 464(3)
Patrick Kupelian
Twyla Willoughby
Targeted Lymph Node Irradiation: Case Study 467(8)
Steven L. Hancock
Todd Pawlicki
Raymond Tan
ProstaScint-Guided IMRT: Case Study 475(6)
Ashesh B. Jani
John C. Roeske
Intra-Prostatic Boost: Emerging Technology 481(5)
Maria T. Guerrero Urbano
Catharine Clark
Chris M. Nutting
David P. Dearnaley
Repair of Unacceptable Implants: Emerging Technology 486(6)
X. Allen Li
Jian Z. Wang
Gynecologic Cancer: Overview 492(43)
Loren K. Mell
John C. Roeske
Neil Mehta
Arno J. Mundt
Cervical Cancer: Case Study 506(7)
Tracey E. Schefter
Brian D. Kavanagh
Endometrial Cancer: Case Study 513(5)
Anuja Jhingran
Mohammad Salehpour
Brooke Brooks
Cervical Cancer Not Suitable for Brachytherapy: Case Study 518(5)
Philip Chan
Michael Milosevic
Janet Paterson
Inhwan Yeo
Anthony W. Fyles
Bone Marrow-Sparing IMRT: Emerging Technology 523(8)
John C. Roeske
Anthony E. Lujan
Arno J. Mundt
Applicator-Guided IMRT: Emerging Technology 531(4)
Daniel A. Low
Lymphoma: Overview 535(21)
Billy W. Loo Jr
Richard T. Hoppe
Hodgkin's Disease: Case Study 547(6)
Billy W. Loo Jr
Richard T. Hoppe
Helical Tomotherapy
A New Mantle: Emerging Technology 553(3)
James S. Welsh
Christopher Peterson
Brad Kahl
Gustavo Olivera
Sarcoma: Overview 556(17)
Kaled M. Alektiar
Linda Hong
Paraspinal Soft Tissue Sarcoma: Case Study 562(6)
Brian O'Sullivan
Ramani Ramaseshan
Mohammad Islam
Robert Heaton
Retroperitoneal Sarcoma: Case Study 568(5)
John B. Fiveash
Richard A. Popple
Martin J. Heslin
Pediatric Tumors: Overview 573(20)
Shiao Y. Woo
Retinoblastoma: Case Study 579(5)
Robert S. Lavey
Arthur J. Olch
Neuroblastoma: Case Study 584(4)
Robert S. Lavey
Arthur J. Olch
Rhabdomyosarcoma: Case Study 588(5)
Joseph K. Salama
Philip P. Connell
Metastatic and Recurrent Tumors: Overview 593(22)
Johnny Kao
Arno J. Mundt
Recurrent Spinal Metastasis: Case Study 599(5)
Stefanie Milker-Zabel
Recurrent Nasopharyngeal Cancer: Case Study 604(5)
Wei-Yuan Mai
Tai-Xiang Lu
Xiao-Wu Deng
Intensity-Modulated Radiosurgery for Spinal Metastasis: Emerging Technology 609(6)
Fang-Fang Yin
Samuel Ryu
Jae Ho Kim
IV. Invited Commentaries
Intensity-Modulated Proton Therapy 615(7)
Tony Lomax
Eros Pedroni
Doelf Coray
Gudrun Goitein
Martin Jermann
Biologic Modifiers and IMRT 622(6)
Kenneth Dornfeld
John Buatti
Pros and Cons of IMRT: What's Been Swept Under the Rug? 628(11)
Roberto J. Santiago
Eli Glatstein
Index 639
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