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简介
吴巍、张玉祥主编的《分子生物学》为“医学教育改革系列教材”（英文版）之一。 分子生物学是从分子水平上研究生命现象物质基础的学科。《分子生物学》系统论述细胞成分的物理、化学的性质和变化以及这些性质和变化与生命现象的关系，如遗传信息的传递，基因的结构、复制、转录、翻译、表达调控和表达产物的生理功能，以及细胞信号的转导等。本教材主要面向在我国接受医学教育的海外留学生和接受双语教学的本科生。
目录
Chapter 1 Historical Review of Molecular Biology
1.1 Definition of Molecular Biology
1.2 Brief History of Molecular Biology
1.3 Basic Content of Molecular Biology
1.4 Role of Molecular Biology in Medical Science
Chapter 2 Transmission of Genetic Information
2.1 DNA Replication
2.2 Transcription
2.3 Translation
Chapter 3 Gene Regulation
3.1 Gene Regulation in Prokaryotes
3.2 Gene Regulation in Eukaryotes
3.3 Noncoding RNA and RNA Interference
3.4 Epigenetic Regulation of Gene Expression
3.5 Gene Regulatory Network
Chapter 4 DNA Damage and Repair
4.1 Factors Causing DNA Damage
4.2 Types of DNA Damage
4.3 DNA Repair Mechanisms
4.4 DNA Damage Caused Effects
Chapter 5 Protein Modification, Trafficking and Degradation
5.1 Folding of Nascent Polypeptide Chains
5.2 Assembly of Protein Subunits
5.3 Posttranslational Modifications of Proteins
5.4 Transport and Localization of Proteins
5.5 Degradation of Cellular Proteins
5.6 Clinical Significance of Protein Modification, Trafficking and Degradation
Chapter 6 Molecular Cloning and Genetic Engineering
6.1 Cloning Enzymes
6.2 Cloning Vectors
6.3 Principle and Procedures of Molecular Cloning
6.4 Genetic Engineering
Chapter 7 Gene Characterization and Functional Analysis
7.1 Nucleic Acid Molecular Hybridization
7.2 Polymerase Chain Reaction
7.3 Nucleic Acid Sequencing
Chapter 8 Omics and System Biology
8.1 Genomics
8.2 Transcriptomics
8.3 Proteomics
8.4 Metabolomics
Chapter 9 Gene Transfer and Gene Targeting
9.1 Gene Recombination
9.2 Gene Transfer and Transgenic
9.3 Gene Targeting by Homologous Recombination
9.4 Transgenic and Its Application
Chapter 10 Molecular Biology of Cancer
10.1 Cell Cycle and Apoptosis
10.2 Oncogenes and Tumor Suppressor Genes
10.3 Molecular Basis of Cancer Development
1.1 Definition of Molecular Biology
1.2 Brief History of Molecular Biology
1.3 Basic Content of Molecular Biology
1.4 Role of Molecular Biology in Medical Science
Chapter 2 Transmission of Genetic Information
2.1 DNA Replication
2.2 Transcription
2.3 Translation
Chapter 3 Gene Regulation
3.1 Gene Regulation in Prokaryotes
3.2 Gene Regulation in Eukaryotes
3.3 Noncoding RNA and RNA Interference
3.4 Epigenetic Regulation of Gene Expression
3.5 Gene Regulatory Network
Chapter 4 DNA Damage and Repair
4.1 Factors Causing DNA Damage
4.2 Types of DNA Damage
4.3 DNA Repair Mechanisms
4.4 DNA Damage Caused Effects
Chapter 5 Protein Modification, Trafficking and Degradation
5.1 Folding of Nascent Polypeptide Chains
5.2 Assembly of Protein Subunits
5.3 Posttranslational Modifications of Proteins
5.4 Transport and Localization of Proteins
5.5 Degradation of Cellular Proteins
5.6 Clinical Significance of Protein Modification, Trafficking and Degradation
Chapter 6 Molecular Cloning and Genetic Engineering
6.1 Cloning Enzymes
6.2 Cloning Vectors
6.3 Principle and Procedures of Molecular Cloning
6.4 Genetic Engineering
Chapter 7 Gene Characterization and Functional Analysis
7.1 Nucleic Acid Molecular Hybridization
7.2 Polymerase Chain Reaction
7.3 Nucleic Acid Sequencing
Chapter 8 Omics and System Biology
8.1 Genomics
8.2 Transcriptomics
8.3 Proteomics
8.4 Metabolomics
Chapter 9 Gene Transfer and Gene Targeting
9.1 Gene Recombination
9.2 Gene Transfer and Transgenic
9.3 Gene Targeting by Homologous Recombination
9.4 Transgenic and Its Application
Chapter 10 Molecular Biology of Cancer
10.1 Cell Cycle and Apoptosis
10.2 Oncogenes and Tumor Suppressor Genes
10.3 Molecular Basis of Cancer Development
Molecular Biology
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