Peptides : biology and chemistry : proceedings of the 10th Chinese International Peptide Symposiu...

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作   者:edited by Yan-Mei Li, Chuan-Guang Qin.

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ISBN:9787122059659

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简介

the 10th chinese international peptide symposium (cps-2008), hosted by tsinghua university and northwestern polytechnical university, was held at xi’an, china, july 1−5, 2008 with more than 200 participants. the four-day conference was both intense and spiritually rewarding. our goal for cps-2008 was to provide a forum for the exchange of knowledge, cooperation and friendship between the international and chinese scientific communities in peptide sciences. the symposium consisted of 14 sessions with 68 oral and 90 poster presentations, including synthetic methods, molecular diversity and peptide libraries, structure and conformation of peptides and proteins, bioactive peptides, peptide immunology, denovo design and synthesis of proteins and peptides, ligand-receptor interactions, the chemistry-biology-interface and challenging problems in peptides. the enthusiastic cooperation and excellent contributions were gratifying and the active response of the speakers contributed to the success of the symposium. the presentations were of excellent caliber and represented the most current and significant aspects of peptide science. we greatly appreciate the generous financial assistance of the sponsors and donors, especially the national natural science foundation of china, whose support was indispensable to make the meeting a great success.

目录

Session 1 Proteomics/Analytical/Structure 1
Interaction of Local Anesthetic Drugs and Na+ Channel Inactivation Gate Peptide in Linker between Domain III and IV by Electrospray Tandem Mass Spectrometry and Surface Plasma Resonance 3
  Bih-Show Lou, Pei-Shan Wu, Yuan-Chin Chen, and Hui-Fen Wu
Femtosecond Two-dimensional Infrared Spectroscopy can be Used to Differentiate Antiparallel from Parallel -sheet Conformations 8
  Jianping Wang
On-line High-performance Liquid Chromatography/ Mass Spectrometric Investigation of the Syntheses of KLVFF and DLVPL Peptides 13
  Qing Zeng
Self-assembly Structure of Oligopeptide Studied by Using Scanning Tunneling Microscopy 20
  Lin Niu, Xiaojing Ma, Xiaobo Mao , Lei Liu , Chen Wang
Session 2 Peptide Synthesis 25
Synthesis and Evaluation of Antitumor Activity of Sansalvamide Analogue 27
  Xia Tian, Yihua Yang, Xiaoli Zhen, Shouxin Liu, Xiaojie Zhang
Synthesis of Zygosporamide Cyclic Peptide 30
  Yihua Yang, Jianrong Han, Shouxin Liu, Jiangchao Wang, Yachao Zhu
The Application of Cross-Mated Strategy between Boc and Fmoc Chemistry in Peptide Synthesis 33
  Xiao-Xiao Yang, Hao Lin, Xiang Han, He-He Feng, De-Xin Wang
Synthesis of Functionalized 2,5-Diketopiperazines from C-phenacyl Ester Protected Dipeptides 38
Hao Lin, Dexin Wang
Synthesis of A Dual-Peptide Jointed by Diketopiperazine Ring 42
  Xiang Han, Hao Lin, De-Xin Wang
Transfer Active Ester Condensation: An Efficient Technology Used for Long Chain Peptide, Branch Peptide and Peptide C-terminal Derivative Synthesis 47
  Yanli Chen, Pu Wang
Biomimetic Synthesis of Gramicidin S from Linear Pentapeptide Precursor on Safety-catch Resin 51
  Chuanguang Qin, Ruijie Zhang, Yan Ding, Weining Niu, Xiaoya Shang, Liheng Wang , Yang Li
Suppression and Application of Some Side Reactions in Peptide Synthesis 57
  Yun-hua Ye
Preparation of A Novel Compound and Its Application in Liquid Phase Peptide Synthesis and Purification 63
  Zhi-Ping Huang, Ming Zhang
Recent Developments in Microwave Enhanced Solid Phase Peptide Synthesis 67
  Jonathan Collins, Michael J. Collins Jr., Sandeep K. Singh, Grace Vanier, Hillary Merriweather, Alicia Douglas, Zachary J. Cox, and Bo Jiang
Fast Automated Conventional Fmoc Solid Phase Peptide Synthesis of Human -Amyloid (1-42) 74
  German Fuentes, Christina A. Hood, Hirendra Patel, Mahendra Menakuru, Jae H. Park
Stepwise Solid Phase Synthesis of Long and Difficult Peptides 82
  Haitao Wang, Mochu Wei, Sheng Chen, Lanlan You, Zhenya Wang, Zilu Tan, Jie Zhao, Fang Yu, Shangshan Chen, Wentao Zhang
A Scale-up Preparation of RTD-1 Peptide Using Solid Phase and Solution Phase Synthesis 91
  Hengwei Chang and Wei Wang
Session 3 Peptide Towards the Clinic 99
Exploring New Approaches to the Treatment of Prolonged Pain: Neuroplasticity, Disease, and Drug Design 101
  Victor J. Hruby, Takashi Yamamoto, Padma Nair, Deepika Laddu, Shou-Wu Ma, Tally Largent-Milnes, Peg Davis, Todd Vanderah, Josephine Lai, Richard Egleton, and Frank Porreca
Structure-Activity Relationships of Peptide and Small Molecule of a-MSH Analogues Targeting the Human Melanocortin Receptors 106
  Minying Cai, Yingkui Yang, Erin Palmer, Matt Dedek, Victor J. Hruby
Session 4 Peptide and Amyloid Disease 109
Amyloid Diseases and Their Inhibitors 111
  Weiwei Li, Meisha Chen
Copper (II) Modulates the Aggregation of A Peptide from the Fourth Repeat of Tau 118
  Chun-Hui Yu, Yan-Mei Li
Session 5 Peptide-based Biomaterials 127
Isolation and Characterization of Potent Antibiotic Peptides from Potato Tubers (Solanum tuberosum L cv. Gogu Valley) 129
  Jong-Kook Lee, Nari Jeong, Byung Kwan Son, Joon Soo Hahm, Yoonkyung Park, and Kyung-Soo Hahm
Antibiotic Activity of Novel Synthetic Peptides Against Pathogenic and Antibiotic Resistant Microorganisms Isolated from Gallbladder Bile in Patients with Cholelithiasis 133
  Jong-Kook Lee, Nari Jeong, Byung Kwan Son, Joon Soo Hahm, Yoonkyung Park, and Kyung-Soo Hahm
Fungicidal Effect of Rice Pex5p, A Receptor for Peroxisomal Matrix Proteins 137
  Seong-Cheol Park, Yoonkyung Park, and Kyung-Soo Hahm
Antibiotic Effect of Antimicrobial Peptide HPA3 against Multi- Drug Resistant Bacteria from Otitis Media 142
  Hae-Kyun Park, Yoonkyung Park, Chul Ho Jang, and Kyung- Soo Hahm
Purification, Isolation and Characterization of Pr-1, A Novel Antifungal Protein, from Pumpkin Rind 145
  Seong-Cheol Park, Jin-Young Kim, Hyeonsook Cheong, Yoonkyung Park, Kyung-Soo Hahm
Session 6 Miscellaneous 149
Exendin-4 Induction of Gene Expression in RINm-5F beta-cells 151
  Jiayi Yua, Di Wang, Jie Chen, Lifeng Wang, Wei Li
Monomeric Insulin with Mutation at B22 Arginine 156
  Ting Chen and Youshang Zhang

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