口腔生物学基础
作者： 陈万涛
出版社：科学出版社 2014-9-12
简介：PREFACECHAPTER Ⅰ MOLECULAR REGULATION OF TOOTH DEVELOPMENT AND DENTAL STEM CELLS 001PART Ⅰ TOOTH DEVELOPMENT 001PART Ⅱ MOLECULAR REGULATION OF TOOTH DEVELOPMENT 0022.1 Initiation of the Tooth 0022.2 Bud-to-cap Transition 0032.3 Condense of Mesenchyme 0042.4 Enamel Knot And Tooth Type Determination 0042.5 The Homeobox Code 0052.6 Hard Tissue Formation 006PART Ⅲ DENTAL STEM CELLS 0073.1 Different Populations of Dental Stem Cells with Diverse Potential 0083.2 Tooth Tissue Regeneration 010REFERENCES 012CHAPTER Ⅱ BIOLOGICAL BASIS IN THE DEVELOPMENT AND REMODELING OF JAWS 014INTRODUCTION 014PART Ⅰ CHEMICAL COMPOSITION OF JAWS 0151.1 Inorganic Components 0151.2 Organic Components 015PART Ⅱ BIOLOGICAL BASIS ASSOCIATED WITH THE DEVELOPMENT OF JAW 0162.1 Bone Development 0162.2 Processes of Bone Development 019PART Ⅲ BIOLOGICAL BASIS ASSOCIATED WITH THE REMODELING OF JAWS 0233.1 Features of Bone Remodeling 0233.2 Cytological Basis of Bone Remodeling 024REFERENCES 026CHAPTER Ⅲ THE IDENTIFICATION OF GENES RELATED TO ORAL HEREDITARY DISEASE 028PART Ⅰ FOREWORD 0281.1 The Concept of Medical Genetics 0281.2 The Characteristics of Oral And Maxillofacial Genetic Diseases 029PART Ⅱ THE CLASSIFICATION OF GENETIC DISEASES 0302.1 Single-gene Disease 0302.2 Mitochondrial Inherited Disease 0302.3 Chromosomal Disease 0312.4 Polygenic Disease 032PART Ⅲ CONFIRMATION OF PATHOGENIC GENES IN MONO-GENE DISEASES 0323.1 Family Pedigree Analysis in Mono-gene Diseases 0333.2 Disease Gene Mapping 0353.3 Genetic Polymorphism And Mutation 035PART Ⅳ ORAL GENETIC DISEASES AND CONGENITAL DISORDERS 0364.1 Genetic Diseases in Dental Hard Tissues 0364.2 Genetic Diseases in Periodontal Tissues 0394.3 Genetic Diseases in Oral Bone Tissues 0424.4 Congenital Facial Cleft 043REFERENCES 050CHAPTER Ⅳ ORAL ECOSYSTEM AND THE INFLUENTIAL FACTORS 053PART Ⅰ ECOSYSTEM AND ECOLOGY 0531.1 Oral Micro-ecosystem 0531.2 The Influential Factors of Oral Micro-ecosystem 054PART Ⅱ DENTAL PLAQUE BIOFILM 0572.1 The Formation of Dental Plaque Biofilm 0582.2 The Classification of Plaque Biofilm 0592.3 The Components of Plaque Biofilm 060PART Ⅲ BIOFILM DISEASE IN ORAL CAVITY 0603.1 The Related Microflora of Dental Caries 0613.2 The Related Microflora of Periodontal Diseases 0633.3 The Progress in Oral Micro-ecosystem Research 065REFERENCES 067CHAPTER Ⅴ TECHNOLOGY AND APPLICATION OF ORAL TISSUE ENGINEERING 069PART Ⅰ THE CONCEPT OF ORAL TISSUE ENGINEERING 0691.1 Biomaterials 0691.2 Seed Cells 0711.3 Growth Factors 072PART Ⅱ APPLICATION OF TISSUE ENGINEERED SKIN AND MUCOSA 0732.1 Tissue Engineered Skin 0732.2 Tissue Engineered Mucosa 075PARTⅢ APPLICATION OF TISSUE ENGINEERED BONE 0763.1 Cell Sources for Bone Regeneration 0763.2 Growth/transcription Factors for Bone Regeneration 0763.3 Biomaterials for Bone Regeneration 0763.4 Pre-clinical Animal Model Research for Bone Regeneration 0773.5 Clinical Translational Researches for Bone Regeneration 078PART Ⅳ FUTURE PERSPECTIVES 0784.1 Strategies for Neovascularization 0784.2 Strategies for Osseointegration 0794.3 Strategies for Tissue Engineered Tooth 079REFERENCES 081CHAPTER Ⅵ CHARACTERISTICS AND APPLICATION OF NEW DENTAL MATERIALS 082PART Ⅰ NEW DENTAL FILLING MATERIAL AND THEIR CHARACTERISTICS 0821.1 Dental Filling Materials 0821.2 Composition And Properties of Dental Filling Materials 082PART Ⅱ CHARACTERISTICS AND APPLICATION OF BIOLOGICAL CERAMIC 0842.1 Species of Biological Ceramic 0842.2 Structure And Properties of Biological Ceramics 085PART Ⅲ EVALUATION OF BIOCOMPATIBILITY AND THEIR CHARACTERISTICS OF NANO-DENTAL MATERIALS 0863.1 Conception of Nano-dental Materials 0863.2 Composition And Properties of Nano-dental Materials 0863.3 Species of Nano-dental Materials 0873.4 Safety Evaluation of Nano-dental Materials 087PART Ⅳ NANOMETER TECHNOLOGIES OF METAL IMPLANT MATERIALS 0884.1 Species of Nanometer Technologies of Metal Implant Material 0884.2 Characteristics of Nanometer Technologies of Metal Implant Material 089REFERENCES 089CHAPTER Ⅶ THE GENETIC AND EPIGENETIC ALTERATIONS IN ORAL SQUAMOUS CELL CARCINOMA 091INTRODUCTION 091PATT Ⅰ GENETIC ALTERATIONS IN ORAL SQUAMOUS CELL CARCINOMA 0921.1 Chromosome Abnormalities And Microsatellite Instability 0921.2 Inherited Genetic Gactors 0961.3 Abnormal Gene And Protein Expression 0991.4 Somatic Mutations in OSCC 102PART Ⅱ EPIGENETIC ALTERATIONS IN OSCC 1022.1 DNA Methylation 1022.2 Histone Modifications 104REFERENCES 105CHAPTER Ⅷ THE BIOLOGICAL CHARACTERISTICS AND SIGNAL PATHWAYS INORAL CANCER 108PART Ⅰ CELL PROLIFERATION AND APOPTOSIS 1081.1 Preface 1081.2 Signal Transduction of Cell Proliferation And Apoptosis 1091.3 Regulation of Cancer Cell Proliferation And Apoptosis 1111.4 Apoptosis Targeted Therapy in Oral Cancer 113PART Ⅱ CELL DIFFERENTIATION AND DEDIFFERENTIATION 1132.1 Concepts of Cell Differentiation And Dedifferentiation 1132.2 Regulation Mechanisms of Cell Di
