Regulation of gene expression : molecular mechanisms /

光盘

作者：  by Gary H. Perdew, John P. Vanden Heuvel, Jeffrey M. Peters.

出版社：

简介："Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms that may result in altered activityof a specific cell protein." "Each of three sections explores mechanisms of gene regulation and expression, andpresents methods and protocols for achieving specific experimental goals. Part I focuses on approaches for studying control of mRNA expression and determining targetgenes for a given transcription copy. Part II outlines themethods for determining how proteins can regulate each other by mediating synthesis, degradation, protein-proteininteractions, and posttranslational modification. Part IIIexplores how gene targeting techniques in mice can provideinsight into protein function. This volume provides a clear, concise overview of the protocols and techniques used to examine chemically or disease-mediate alterations in gene expression in mammalian systems."--BOOK JACKET